Fantasy grade, projections, percentile rankings, advanced usage, and weekly points.
Isaac Guerendo is a fantasy running back and is a fantasy running back for the 2026 season.
Isaac Guerendo is an NFL running back for SF. Not currently on the fantasy radar. One to monitor for a changing role. Currently listed as PUP, so check his status before locking your lineup.
NR · Unranked. Not currently on the fantasy radar. One to monitor for a changing role. Currently listed as PUP, so check his status before locking your lineup.
Athletic profile: Isaac Guerendo ran a 4.33-second 40-yard dash (99th percentile at RB), a 41.5-inch vertical, a 129-inch broad jump, for a composite athletic score of 88 out of 100. Drafted in 2024 (Round 4, Pick 129) out of Louisville.
| Season | G | Rush | Rush Yd | TD | Rec | Rec Yd | PPG |
|---|---|---|---|---|---|---|---|
| 2025 | 14 | 0 | 0 | 0 | 0 | 0 | 0.1 |
| 2024 | 16 | 84 | 420 | 4 | 15 | 152 | 5.9 |
Isaac Guerendo is not currently ranked among draftable fantasy running backs, so treat him as a late-round flier or watch-list add for 2026.
Isaac Guerendo does not have an early-round consensus ADP right now, so in most 12-team leagues he is a late-round pick or waiver-wire add rather than a core draft target.
Isaac Guerendo is currently listed as PUP. Check his game-day status before locking your lineup.
Not currently on the fantasy radar. One to monitor for a changing role. Currently listed as PUP, so check his status before locking your lineup.